The second weekend of January delivers one of the most anticipated betting slates of the year. NFL Wild Card Weekend opens the postseason with win-or-go-home matchups while the College Football Playoff Semifinals bring National Championship implications to Thursday night. Add in marquee college basketball, a solid NBA and NHL weekend, international tennis, and English FA Cup action, and bettors have no shortage of opportunities across multiple sports.
Top Sports for the Weekend — MyBookie
NFL Wild Card Round — January 10–12, 2026
Los Angeles Rams at Carolina Panthers — 4:30 PM ET (Sat) — The Rams are -10 favorites to take down the Panthers in Carolina. Bryce Young and his buds upset LAR during the regular season with the second fave tow in the Lombardi exact revenge or will history repeat?
Green Bay Packers at Chicago Bears — 8:00 PM ET (Sat) — A classic NFC North rivalry takes center stage at Soldier Field. The Bears have flipped from +1.5 home dogs to -1 favorites. The Packers D must step it up big time to contain Chicago’s rushing attack.
Buffalo Bills at Jacksonville Jaguars — 1:00 PM ET (Sun) — Josh Allen is going to have to be Superman if the Bills hope to escape Jacksonville with a win. The Jags are on an 8-game winning streak where the defense has dominated and Trevor Lawrence and the offense have looked unstoppable. Jags ML might be the play of the week.
San Francisco 49ers at Philadelphia Eagles — 4:30 PM ET (Sun) — The good feelings around San Francisco have dissipated. The line opened Eagles -3.5 and has risen a full point to Birds -4.5. If Trent Williams doesn’t play, the Niners are going to find it difficult to keep the Eagles’ D line away from Brock Purdy.
Los Angeles Chargers at New England Patriots — 8:20 PM ET (Sun) — John Harbaugh brings a solid Chargers’ squad to town to face likely NFL MVP Drake Maye and the Patriots. How will LAC’s patched together offensive line handle New England’s pass rush? Can Maye perform magic versus the Bolts’ defense?
Houston Texans at Pittsburgh Steelers — 8:15 PM ET (Mon) — The Texans are -3.5 road favorites versus the home team Steelers. Aaron Rodgers gets D.K. Metcalf back. Also, Pittsburgh’s D has been excellent versus the rush, which bodes well for the home dog.
College Football Playoff Semifinals
Miami Hurricanes vs Ole Miss Rebels — Thursday, January 8 — No. 10 Miami faces No. 6 Ole Miss in a semifinal matchup that contrasts Miami’s incredible defense versus Trinidad Chambliss and Ole Miss’ O. The Canes are the -3.5 favorite in a game that offers overlay odds on under the 52.5 total.
Oregon Ducks vs Indiana Hoosiers — Thursday, January 8 — The two top quarterbacks in college football clash when Oregon’s Dante Moore goes mano y mano again versus Indiana’s Fernando Mendoza. The Hoosiers’ QB won the first duel. Will Moore get it done in the rematch?
Men’s College Basketball — Saturday, January 10
Tennessee Volunteers at Florida Gators — Tennessee travels to Florida in a key SEC matchup. The defending champs, that’s the Gators, have fallen out of the Top 25. A win over ranked Tennessee could send them back into the poll.
Wisconsin Badgers at Michigan Wolverines — Wisconsin faces a major road test against No. 2 Michigan. The Wolverines have their sights set on the top spot in the polls. Beating Wisconsin is necessary to get it done.
SMU Mustangs at Duke Blue Devils — No. 24 SMU visits No. 6 Duke in a game between two Top-25 teams. The Stangs will be looking to make as statement while the Devils hope to continue their consistent play.
Arizona Wildcats at TCU Horned Frogs — No. 1 Arizona hits the road to face TCU in a key Big 12 matchup. Zona plans on keeping their undefeated record intact while the Frogs look to upset the nation’s top squad.
Arkansas Razorbacks at Auburn Tigers — No. 15 Arkansas takes on Auburn in an early season SEC battle. The Tigers have fallen out of the Top 25. A win over the John Calipari led Hogs could land them back into the polls.
NBA Weekend Spotlight
The NBA schedule highlights two key Sunday matchups. San Antonio travels to Minnesota in a game where no doubt Ant Edwards will shine. This is especially true because Wemby is likely to sit for the Spurs. Later, Giannis Antetokounmpo leads Milwaukee into Denver to play in a marquee matchup that lacks star power due to Nikola Jokic’s injury.
NHL Weekend Highlight
Saturday’s NHL slate features two notable matchups. The New York Rangers visit the Boston Bruins in a rivalry game that often produces tight scoring and physical play. Later, the Los Angeles Kings travel to Edmonton to face the Oilers in what promises to be a wild Western Conference throw down.
2026 Brisbane International
The Brisbane International continues this weekend as players prepare for the Australian Open. The outdoor hard-court event provides daily betting opportunities across ATP and WTA matches, with early rounds often offering value in set and live markets.
English FA Cup
FA Cup Third Round matches take place Saturday, January 10, as Premier League clubs enter the competition against English Championship squads. Rotation and motivation can vary widely, creating betting opportunities across goal totals and match results.
From the NFL Playoffs to the College Football Playoff Semifinals and a full slate of college basketball, this weekend offers bettors one of the most diverse boards of the season. NBA, NHL, tennis, and FA Cup action round out a global schedule that rewards preparation and discipline. With so much on the board, smart line shopping and bankroll management are essential heading into one of the busiest weekends of the New Year.
