Top Sports for the Weekend — October 23–27, 2025
It’s one of those weekends that sports fans dream about. Major matchups in NFL and NCAAF, the 2025 World Series throws first pitch, a UFC Heavyweight Title fight in Abu Dhabi, and races roaring in Mexico and Ricky Bobby’s favorite track, Talladega.
Let’s run through everything happening from Thursday, October 23 through Monday, October 27, 2025!
Betting Recap & Sports Update for the Week with MyBookie
Check out this weekend’s top sports events.
NFL Week 8 — 2025
All times ET unless noted.
Thursday, October 23
Minnesota Vikings at Los Angeles Chargers
The Chargers return home under the lights looking to steady their fast-sinking ship while the Vikings try to prove they can get back on track after a brutal loss to the Eagles.
Thursday Night Football kicks off NFL Week 8 with playoff energy early in the season.
Sunday, October 26
- Miami Dolphins at Atlanta Falcons
- Chicago Bears at Baltimore Ravens
- Buffalo Bills at Carolina Panthers
- New York Jets at Cincinnati Bengals
- San Francisco 49ers at Houston Texans
- Dallas Cowboys at Denver Broncos
- Cleveland Browns at New England Patriots
- Tampa Bay Buccaneers at New Orleans Saints
- Tennessee Titans at Indianapolis Colts
- Green Bay Packers at Pittsburgh Steelers
Each game on the Sunday slate carries playoff implications. Lamar Jackson should return in Baltimore, making the Ravens-Bears matchup massive. The Panthers are no longer pushovers, Cincy has a new pilot in 40-year-old Joe Flacco, and the Niners keep winning despite key injuries.
Aaron Rodgers takes on his former team when Green Bay heads to Pittsburgh, and the Cowboys dance with the Broncos in Denver. NFL Sunday Week 8 is going to be awesome!
Monday, October 27
Washington Commanders at Kansas City Chiefs
The Chiefs close the week on Monday night, hosting a Washington team fighting through major injuries.
Can former star QB Marcus Mariota keep up with scorching Patrick Mahomes and the KC offense?
College Football — Saturday, October 25
A loaded slate of conference showdowns and road warrior underdogs with upset potential highlight the college gridiron board:
- UCLA Bruins at Indiana Hoosiers
- Ole Miss Rebels at Oklahoma Sooners
- South Florida Bulls at Memphis Tigers
- Alabama Crimson Tide at South Carolina Gamecocks
- Missouri Tigers at Vanderbilt Commodores
- BYU Cougars at Iowa State Cyclones
- Texas A&M Aggies at LSU Tigers
Consider backing road teams with value, like Ole Miss versus Oklahoma, or home programs needing a statement, such as LSU hosting the Aggies. South Florida at Memphis could decide the AAC title, while Alabama might roll as -12 road chalks versus LaNorris Sellers’ Gamecocks. Undefeated BYU could be due for a loss visiting a tough Cyclones squad as a +3 dog.
NBA Weekend Spotlight
The 2025–26 NBA season is officially underway, and early trends are already forming.
NBA Weekend Highlight Game:
Milwaukee Bucks at Cleveland Cavaliers – Sunday, October 26
If the Cavaliers are going to reach the NBA Finals, this is their proving season. Donovan Mitchell and the Cavs can make a statement against Giannis Antetokounmpo and the Bucks when Milwaukee visits Cleveland on Sunday.
NHL Game of the Week
Vegas Golden Knights at Florida Panthers – Saturday, October 25
Defending Stanley Cup Champion Florida hosts potential 2026 Finals opponent Vegas in a West vs East clash. This early-season test could set the tone for both contenders moving into November.
UFC 321: Aspinall vs Gane — Saturday, October 25
Tom Aspinall defends his heavyweight crown against Ciryl Gane in the main event at UFC 321 in Abu Dhabi.
The event starts early, at 10:00 AM ET, due to the time difference, so get your bets in before breakfast and coffee!
F1 and NASCAR — Sunday, October 26
Formula 1: Mexico City Grand Prix
With five races remaining, Max Verstappen and Red Bull have begun to surge. McLaren’s Oscar Piastri and Lando Norris aim to hold off Max and keep McLaren in front for the Constructors’ and Drivers’ titles.
NASCAR Playoffs: Talladega Superspeedway
Chase Briscoe, Denny Hamlin, Christopher Bell, and Kyle Larson lead the NASCAR Playoff Standings. William Byron and Joey Logano hope to close the gap at one of NASCAR’s most iconic and unpredictable tracks.
⚾ MLB — 2025 World Series: Dodgers vs Blue Jays
The 2025 World Series begins Friday, October 24 in Toronto.
- Game 1: Friday, October 24 – Rogers Centre, Toronto
- Game 2: Saturday, October 25 – Rogers Centre, Toronto
- Game 3: Monday, October 27 – Dodger Stadium, Los Angeles
The Dodgers are heavy -220 favorites to become the first back-to-back World Series champions since the Yankees (1999–2000). Led by Shohei Ohtani, L.A. looks unstoppable, but Vladimir Guerrero Jr. and the Jays are far from done.
This Weekend’s Bottom Line
From World Series drama to Sunday gridiron wars, this weekend delivers wall-to-wall action. Whatever your playstyle, MyBookie has every angle covered — pick your spots, trust your handicapping, and cash in on one of the most stacked sports weekends of the year.
Bet on Sports: Access updated sportsbook odds and wager live all weekend long with MyBookie.